Small molecule JNK (c-Jun N-terminal kinase) inhibitors

J Med Chem. 2010 Apr 22;53(8):3005-12. doi: 10.1021/jm9003279.
No abstract available

MeSH terms

  • Allosteric Regulation
  • Animals
  • Cardiovascular Diseases / enzymology
  • Crystallography, X-Ray
  • Humans
  • Inflammation / enzymology
  • Inflammation / immunology
  • Isoenzymes / antagonists & inhibitors
  • Isoenzymes / chemistry
  • JNK Mitogen-Activated Protein Kinases / antagonists & inhibitors*
  • JNK Mitogen-Activated Protein Kinases / chemistry
  • JNK Mitogen-Activated Protein Kinases / physiology
  • Metabolic Diseases / enzymology
  • Neurodegenerative Diseases / enzymology
  • Protein Conformation
  • Protein Kinase Inhibitors / chemistry
  • Protein Kinase Inhibitors / pharmacology*
  • Signal Transduction

Substances

  • Isoenzymes
  • Protein Kinase Inhibitors
  • JNK Mitogen-Activated Protein Kinases